Thyroid disorders are the most common disorders of the endocrine glands. Increasing incidences of hypothyroidism is a matter of worry; there are many measures to treat the hypothyroidism according to the condition. In case of primary hypothyroidism treatment is to give the hormone. But if this hormone is given for long time there is a great tendency for their thyroid to become progressively less functional and eventually stop producing any functional hormone. The Ayurvedic medicines are useful in the management of hypothyroidism without any side effects. The present case study has focus effectiveness of Ayurvedic therapy in primary hypothyroidism.