Purpose:  To compare the effect of using fibrin glue or 10–0 nylon sutures on the clinical outcome of patients un­dergoing pterygium excision and conjunctival autografting.

Methods: We took 44 patients who underwent pte­rygium excision and conjunctival autografting and were followed up for more than 3 months. The operation duration, postoperative inflammation, complications, and recurrence rates were compared between groups of 21 patients (21 eyes) for whom fibrin glue was used (fibrin glue group) and 23patients (23 eyes) for whom suturing was performed with 10–0 nylon (suture group) in pterygium excision and conjunctival autografting.

Results: The operation duration was 25.45± 4.32 minutes in the fibrin glue group and 42.40 ±7.48  minutes in the suture group (p = 0.0001). Seven days after the operation, the fibrin glue group showed milder conjunctival in­flammation than the suture group (p = 0.000). Postoperative complications and corneal recurrence rates were not statistically different between the two groups.

Conclusions: The use of fibrin glue in pterygium excision with conjunctival autografting is likely to be a more ef­fective, safer procedure than suturing.