IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-6-4-10543 Original Research Paper STUDY OF THERMAL UTERINE BALLOON ABLATION FOR TREATMENT OF SUBJECTS WITH REFRACTORY DYSFUNCTIONAL UTERINE BLEEDING PRESENTING WITH MENORRHAGIA Ritu Jain Dr. Dr Brajendra kumar Dr. April 2017 6 4 01 02 ABSTRACT

 Aim of this  study was to establish the effectiveness of UBT for treatment of refractory DUB over a follow up period of 3 and 6 months & to study the complications of Thermal Uterine Ablation.  This study of effectiveness of Thermachoice UBT system in 30 subjects of refractory DUB (refractive to medical therapy with TxA and/or COCs and/or Progestins) presenting with menorrhagia was carried out in the Department of Obstetrics and Gynaecology, NCH, Surat, from dec’06 to sep’09. After confirmation of the diagnosis and ensuring that the subjects fulfilled the selection criteria, they were subjected to the procedure of Thermachoice UBT in the proliferative phase of the menstrual cycle under appropriate anesthesia (GA or local analgesia with Para cervical block).  28 subjects (93.33%) were in reproductive age group. 29 subjects (96.67%) were multiparous. Average BMI of enrolled subjects was 21.72. All subjects had haemoglobin <12 gm/dL before commencing treatment. 26 subjects(86.67%) had endometrial thickness  ≤10mm at the time of evaluation. Menstrual blood loss was reduced in 22 subjects(~96%) at 3 &6 months follow–up.Minor side effects in post operative period in form of abdominal cramps and low backache were seen in 12 subjects(39.6%), which easily responded to oral analgesics/antipyretics. 76% cases in the present study showed improved QOL, while 12% were neutral in outcome.36% subjects were very satisfied with treatment, 40% satisfied and 12% remained neutral.Incidence of very severe & severe anemia decreased from~4% & ~43% to 0% & 16%, respectively. Incidence of moderate anemia (8.1–10) decreased from 26% before treatment to 24%.Subjects having >10 gm% Hb rose from 26% pre treatment to 52% post treatment. ~83% of the subjects had endometrial atrophy post treatment (ET < 7mm). Uterine Balloon Therapy is an simple, safe, quick, effective & potentially  long term, minimally invasive treatment option for refractory DUB.