Background Rheumatic Heart Disease (RHD) is the most frequent heart disease in children of developing countries, with mitral valve is often affected. Chronic mitral regurgitation causes progressive left ventricular dysfunction, and mitral valve surgery should be performed before the change in left ventricular function. One of the indication for surgery is ejection fraction (EF) < 60% and left ventricular end–systolic diameter (LVESD)  ≥ 40 mm.

Objective To evaluate the relationship between mitral regurgitation severity and left ventricular systolic function

Methods A cross sectional retrospective study was conducted by obtaining medical record data  from Haji Adam Malik Hospital during January 2011 to January 2015. Subject were children with RHD, aged 5 to 18 years old that met the criterias. Complete echocardiography was done in all subjects to evaluate severity of mitral regurgitation, ejection fraction and LVESD. Data were analyzed by calculating Anova, Mann Whitney and Spearman correlation.

Results There was a significant relationship between mitral regurgitation severity and left ventricular systolic function, which only LVESD that showed a significant relationship (P=0.0001), but not in EF (P=0.968). Age was correlate with LVESD in children RHD with mitral regurgitation (P=0.04, r=0.303), but not in sex (P=0.08).

Conclusion There was a significant relationship between mitral regurgitation severity and left ventricular systolic function, which was only seen in LVESD. Age was correlate with LVESD in children PJR with mitral regurgitation.