Aims and objectives – To find out the correlation of serum Vitamin D levels in early pregnancy with subsequent development of preeclampsia (PE).

Material and methods – This observational study was done in Department of Obstetrics & gynaecology, SMS Medical College, Jaipur on 800 pregnant women between 13–20 weeks gestation. Serum Vitamin D levels were assessed, all women were followed till delivery and development of preeclampsia was observed.

Results – Serum 25(OH)D concentrations in early pregnancy were lower in women who subsequently developed preeclampsia as compared to women who did not develop preeclampsia [mean, 13.58 ± 7.61 ng/ml, vs. 17.14±6.91ng/ml, and 95% confidence interval 1.54–5.37; p value< 0.001]. Serum vitamin D levels showed a decrease as the severity of hypertensive disorders increased.

Conclusion – It was thus concluded that Low serum Vitamin D levels were associated with increased incidence of preeclampsia.