IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-6-4-10699 Original Research Paper Isolation and characterization of bioactive principles from leaves of Foeniculum vulgare and effect of anti tubercular perspectives S.D Dr. April 2017 6 4 01 02 ABSTRACT

 Foeniculum vulgare is a perennial herb native to southern Europe and meditteranean sea. Folklore claims states that it has a wide range of biological potentials which are unsung in nature. Preliminary phytochemical screening reveals the chloroform extract of the leaves of Foeniculum vulgare  possess antitubercular perspectives against H37RV (ATCC No: 27294) using MABA method. Chromatographic fractionation of chloroform extract of F.vulgare resulted in the isolation of bioactive compounds such as monoterpene, 1,8 –cineole and estragole. Characterization was performed by interoperating the IR, C18 NMR, H1 NMR & Mass data. MIC of the fractions (hexane: ethylacetate 95:5;85:15;75:25) exhibited at 25µg/mL. Phytochemical qualitative investigations revealed the presence of secondary metabolites such as alkaloids, phenols, glycosides, tannins, saponins and flavanoids.