IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-6-4-10704 Original Research Paper Non functioning Neuroendocrine tumour of pancreas in a 14 year old child A rare case report Y Deshpande Dr. April 2017 6 4 01 02 ABSTRACT

 Introduction– Pancreatic NETs are rare subgroup of pancreatic tumors and represent about 1–2% of all pancreatic neoplasms. The incidence and prevalence of overall NETs has increased substantially Neuroendocrine tumors (NET) account for approximately 25% of pediatric pancreatic masses. NET arise from endocrine tissues of the pancreas and are classified as either non–functioning or functioning. Functioning NETs secrete various peptide hormones, which act at distant sites and can result in a variety of clinical syndromes. Pancreatic NETs can be benign or malignant; however the majority of non–functioning tumors are malignant. Pancreatic tumors in children rarely present with biliary obstruction, owing to the expansive rather than infiltrative growth patterns of the common pediatric pancreatic neoplasms.

Methods A 14 year old male child presented with intermittent jaundice and epigastric pain since 6 months. The patient consulted a local doctor and was initially managed conservatively. As the symptoms persisted he was then referred to our institute. On investigating, Complete blood count was normal

Total bilirubin was 5.2mg/dl with direct of 4.1mg/dl Se Alkaline phosphatase 253 IU/L,SGOT 91,SGPT 67 IU/L,Se.Albumin 2.95gm/d

 

 The USG showed a mass in the head region of pancreas, with dilated common bile duct.

 

 On follow up, abdominal CT scan was requested, which showed a retroperitoneal lesion in the right upper quadrant with a size of7.5 cm×6.6 cm×7 cm with intense peripheral heterogeneous enhancement on arterial phase with gradual central enhancement on delayed phase after administration of contrast media and infiltration of the duodenal wall without invasion of the large vessels, CBD measured 21mm.No evidence of metastasis.