Introduction: 

       Pneumonia associated with mechanical  ventilation  is one of the most important causes of nosocomial infections in paediatric intensive care units . Despite advances in patient care, changing tracheal floras complicate therapy by acquiring drug resistance.

Methods –   The tracheal secretions of  patients   on  mechanical ventilation from   Paediatric–Intensive–Care– received in Microbiology laboratory  were  processed by standard  bacteriological techniques. The correlation  between  the  organisms  isolated from tracheal secretions & organisms causing VAP were studied.

Results : Out of  104 tracheal secretions, 82 (78.84%)  showed the bacterial growth.The  with most common  organism isolated from tracheal secretion of VAP patients was  pseudomonas aeruginosa. A  VAP  rate  of 8.65 % or 17.34 per 1000 ventilator  days was found. Approximately12–  50%  Gram negative bacilli were Multi drug resistant. 

Conclusion– We hope present observation would be helpful in providing useful guidelines for initiation of therapy in patients suspected of developing  VAP.