IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-6-4-10745 Original Research Paper Lower jaw defect anomalyrare first arch syndrome SHARMA Dr. AMRUTHA K V–KUDIL Dr. April 2017 6 4 01 02 ABSTRACT

 Maxillofacial defects are common defects occurring congenitally .First pharyngeal arch, which are composed of mesenchymal cells derived from mesodermal and cranial neural crest cells, give rise to a wide variety of facial structures including skeletal, muscular and neural elements through a complex signaling network still poorly characterized. Cleft of mandible and lower lip are comparatively rare and form severe anomaly amongst this group. Severe and complete division of the mandible is also called as inferior gnathechisis. These defects may be found alone or they may form a part of some syndrome1