IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-6-5-10758 Original Research Paper The Spiel of Fine Needle Aspiration Cytology in The diagnosis of metamorphosis and striding of soft tissue tumoursTwo year study Ragini Thapa Dr. May 2017 6 5 01 02 ABSTRACT

 INTRODUCTION: Fine Needle Aspiration Cytology is well ingrained technique for evaluation of tumors for many years.It has entrenched its place in the diagnostic work up of soft tissue tumors as well. This study professes an assessment of a total of 35 cases of soft tissue tumors by Fine Needle aspiration cytology during a period of two years 2013–2015 and the patients were followed up in accordance for histopathological correlation.Diagnosis and Exemplification of many mass lesions, both superficial and deep–seated, can often be formalized by FNAC.  AIMSAND OBJECTIVES:  The aim of this study is to elucidate the role of Fine Needle Aspiration Cytology in diagnosing various types of soft tissue tumors and the sensitivity, specificity, positive and negative predictive values, and overall histological correlation percentage of Fine Needle Aspiration Cytology in diagnosing soft tissue tumors.  MATERIALS AND METHODS: Aspirations were done using a 22–24 gauge disposable needle and a 5cc to 10c.c disposable syringe for suction. Wet–fixed smears with isopropyl alcohol were stained with hematoxylin and eosin. Dry–fixed smears were stained with Leishman Giemsa along with Pap stain were studied for cytological details and diagnosis. The excised surgical specimen and biopsies of the above cases were processed routinely and stained with Hematoxylin and Eosin.  RESULTS: Total of 35 cases were studied from December 2013 to December 2015 . Out of these we received excised specimen and biopsies for 35 cases. 25 were diagnosed as benign soft tissue tumors, while 10 were diagnosed as malignant on cytological examination. The median age of benign soft tissue tumors was 36 years, while that of malignant soft tissue tumors was 50–60 years. Prevalence was highest in the age group of18–45 years, during which majority were benign lesions. Benign Soft tissuetumors were more common in the upper extremities with predominant , while malignant tumors were more common in the lower extremities and trunk. Sex wise distribution showed a male: female ratio of 1.25:1, indicating that they were more common in males. The most common tumors were lipomas, followed by  nerve sheath tumors. Allusive analysis was done between the cytology report and histopathology.  CONCLUSION: Final evaluation of the results showed that the diagnostic accuracy of FNAC of soft tissue tumors according to the present study was 95.37%, sensitivity was 81.9% and specificity 95.83%. Thus our study proves the efficacy of FNAC in the diagnosis of soft tissue tumors as a useful cost–effective procedure.