IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-6-5-10770 Original Research Paper Impact of donor age on evaluation of renal graft function Roy Dr. Dilip Kumar Pal Dr. May 2017 6 5 01 02 ABSTRACT

 Introduction: In recent times, due to the increasing demands for renal transplant  more elderly donors are being recruited. Contrary to previous notions that kidneys taken from elderly donors function poorly, recent studies have shown otherwise. This study aims to evaluate the elderly donor kidney graft function, by comparing younger donor group(<50 years) with older donor group(>50 years). Materials and methods: A total of 68 donors were taken. They were divided into two groups as per age,<50 years and >50 years. Recipient creatinine and eGFR(by MDRD equation) were obtained in both groups at 1 month,3 months and 6 months after transplant. They were compared and statistical analysis was done to determine any significant difference. Results: Out of the 68 patients, 42 were <50 years of age and 26 were >50 years of age. The mean serum creatinine of recipients in the donor age group of <50 years were 0.97±0.56 mg/dl, 1.00±0.88 mg/dl and 0.99±0.54 mg/dl at 1 month,3 months and 6 months after transplant, and in the group of >50 years were 1.27±0.87 mg/dl, 1.25±0.81 mg/dl and 1.25±0.68 mg/dl at 1 month,3 months and 6 months. The mean eGFR of recipients in the donor age group of <50 years were 68.79±2.78, 68.24±2.01 and 68.57±1.98 at 1 month,3 months and 6 months after transplant, and group of >50 years were 67.55±2.70,67.97±1.99 and 67.72±2.02 at 1 month,3 months and 6 months with no  statistically significant difference.   Conclusion: Elderly donor kidneys can be safely used for transplantation, without any significant deterioration of graft function later on in recipients.