Periodontal disease results from inflammation of the supporting structures of the teeth in response to chronic infections caused by various periodontopathic bacteria. The main goals of periodontal therapy are to eliminate bacterial deposits and niches by removing the supragingival and subgingival biofilms and to restore the biological compatibility of periodontally diseased root surfaces for subsequent attachment of periodontal tissues to the treated root surface. Although SRP produces significant clinical improvements in patients with chronic periodontitis (CP), the complete elimination of bacterial deposits can be difficult to accomplish. To overcome these limitations of conventional mechanical therapy, several adjunctive protocols have been developed. Among these, the use of lasers has been proposed for its bactericidal and detoxification effects and for its capacity to reach sites that conventional mechanical instrumentation cannot.