Atherosclerosis is a major cause for cardiovascular disorders in diabetes and metabolic syndrome. Many risk factors are associated with the metabolic syndrome.(1). The metabolic syndrome occurs in most people with type 2 diabetes, its presence likely accounts for most of the increased incidence of CVD in type 2 diabetes (2). However the presence of diabetes increases the risk of CVD beyond this it is with the metabolic syndrome alone. Moreover CVD risk is increased in type 1 diabetes (3) in which the presence of metabolic syndrome and other risk factors is less common. There is evidence that glucose plays an important role in atherogenesis and also discusses the relative importance of glucose versus lipids. The epidemiological evidence suggests that hyperglycaemia and glycaemic control are CVD risk factors. Many events are involved in the increase of cardiovascular disease (CVD) (1). Most of the people with type 2 diabetes, increases incidence of CVD (2). Beside this CVD risk factor is also seen in type 1 diabetes (3), but it is less common. The type 1 and type 2 diabetes are increased risk factor of atherosclerosis and CVD. Hyperglycaemia which defines the diabetic state and which is common to type 1 and type 2 diabetes.