IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-6-5-10823 Original Research Paper PROSPECTIVE ANALYSIS OF COAGULATION PROFILE IN PREECLAMPSIAECLAMPSIA SYNDROME COMPLICATING PREGNANCY PATIENTS AND ITS CORRELATION WITH FETAL OUTCOMES IN A TERTIARY CARE CENTRE. Muniswamy Dr. E.Pavithra Dr. May 2017 6 5 01 02 ABSTRACT

 Background:Preeclampsia–eclampsia syndrome  complicating pregnant women are at potential risk of developing various coagulation disorders and is one of the major cause of perinatal  morbidity  and  mortality.   Aim:To assess the coagulation profile of patients  having preeclampsia  complicating pregnancy and to compare it with coagulation profile of normal pregnant women . In  addition, to analyse the  effect of  deranged coagulation  profile  with  fetal outcomes.  Methods: Prospective  analysis of  coagulation profile of 60 cases and 60 controls were done and their fetal outcomes were compared. Results :In this present study, there is significant prolongation of clotting time, prothrombin time, activated partial thromboplastin time in preeclampsia–eclampsia group when compared to normotensive pregnant women. This deranged coagulation  profile  had significant association with  unfavourable fetal outcomes. Conclusion:Estimation of coagulation profile will help to identify preeclampsia–eclampsia complicating pregnant women with compromised coagulation status. Thus  identification of such high risk group among preeclampsia–eclampsia complicating pregnant women would help to deliver prompt and effective  medical  care  thereby  reducing  maternal and perinatal morbidity and mortality.