In last few years, prevalence rate of Obesity and overweight has significantly raised in the young generation, especially among the adolescents. The students studying in medical streams also suffer from this health hazard. Objective:To study the association Obesity with Hypertension among first year students of a Medical College. Methodology: The study design was  cross sectional,  comprises 200 1st year medical students of both sexes of Institute of Medical Sciences. BMI was calculated by the formula weight in kg/height2 in meter, and based on the BMI criteria by the World Health Organization, the students were classified into four groups: Underweight, normal, overweight, and obese groups. The blood pressure was measured by sphygmomanometer. Results: The analysis revealed significant association between BMI and both Systolic and Diastolic B.P., both with p value<0.05. Conclusion: The above study reveals a significant association between Obesity and changes in blood pressure in medical students.