The advancement of science has contributed significantly to daily aspects of our lives including both our medical and dental care. Traditionally, apexification was used to treat immature necrotic permanent teeth but with the advancement came a newer technology of regeneration in dentistry. Regenerative endodontic treatment is an advanced procedure designed to replace damaged pulp tissue with viable tissue that can restore the normal function of the pulp–dentin structure. These regenerative endodontic techniques involve the use of stem cells, scaffolds and growth factors. Although with the introduction of regenerative endodontics there have been potential benefits to patients but it still fails to re–establish real pulp tissue. This mini review provides an overview of regenerative endodontics and its goals, and the drawbacks that should be considered to affect the efficiency of the treatment