IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-6-6-11052 Original Research Paper CURCUMIN ORABASE IN THE MANAGEMENT OF ORAL SUBMUCOUS FIBROSIS: A NOVEL APPROACH. Raju Devaraju Dr. Srikanth Goud Gotoor Dr. Tejaswi katne Dr. June 2017 6 6 01 02 ABSTRACT

 Aims and Objectives:  The aim of this study was to evaluate the efficacy of 4% curcumin orabase, in oral submucous fibrosis (OSMF). Materials and Methods: 30 subjects diagnosed with OSMF were included for the study. The patients were administered 4% curcumin orabase (Patent no. 845/CHE/2014) topically three times a day; efficacy of the therapy was evaluated considering the mouth opening and burning sensation of the subjects as parameters. The evaluation was done on a timely basis for a period of three months, and the data was then evaluated. Results: The improvement in mouth opening and the decrease in burning sensation were statistically significant (p<0.0001).  Conclusion: 4% Curcumin orabase can also be considered as a best alternative treatment in OSMF, however, further research is intended on a larger sample size with longer followup.