Introduction: Diabetes mellitus (DM) is a group of metabolic diseases which if not controlled can cause serious complications.  Aim: Magnesium and Electrolyte Profile Evaluation In The Hypoglycemic Type II Diabetic Subjects. Methodology: Fasting blood glucose (FBG), glycated hemoglobin (HbA1c), serum sodium (Na+), potassium (K+) and Magnesium levels were evaluated. Total sample size was 60, which was divided into 30 study group with type II DM having hypoglycemia (blood glucose level <70 mg/dl) who attended the Medicine OPD of AVBRH Hospital and 30 age, sex matched healthy controls included in the study. Results: Serum Sodium and Magnesium levels were significantly lower and the level of serum Potassium were significantly higher in the cases as compared to controls (p<0.0001). Conclusion: Early detection of Magnesium and Electrolyte abnormalities can minimize the risk for development of various diabetic complications in the hypoglycemic type II diabetic subjects.