IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-6-6-11213 Original Research Paper Intracranial Bleed: A study of Clinico–Radiological Profile and Outcome Rathod Dr. Sayali Bhambar Dr. June 2017 6 6 01 02 ABSTRACT

 Introduction: The present study was performed to evaluate the varied clinical presentation, risk factors, clinical and neuro–radiological parameters that would help to predict the outcome of haemorrhagic stroke. Materials & Methods: Present prospective observational study was conducted in department of Medicine of tertiary heath care hospital. A total of 50 consecutive non–traumatic intracranial haemorrhage patients were included after satisfying the inclusion criteria. Detailed history of all the patient was taken along with general, systemic and neurological examination and relevant investigation. Based on the CT brain, history, clinical examination and blood investigations, a final diagnosis was reached. The patients with normal CT findings underwent an MRI Brain or MRA as needed for localisation and confirmation of diagnosis. All the patients were re–evaluated at the time of discharge from the hospital regarding the outcome of the disease, to assess the prognosis and rehabilitation.        Results: Mean age of study subjects was 60.86 ± 11.08 years with Male to female ratio of 1.6:1. Hemiparesis/ Hemiplegia (92%) was the most common presentation followed by headache (82%), vomiting (72%) and sensory loss (52%). Aphasia was present in 44% of patients in present study. Systolic and diastolic blood pressure more than 160 mm and 100 mm of Hg was seen in 76% and 62% patients respectively. History of addiction to alcohol and smoking was seen in 38% and 62% cases while hypercholesterolemia was observed in 44% cases respectively. Intracranial bleed in cerebellum and thalamus was associated with highest mortality while least mortality was found in lobar bleed. The volume of hematoma more than 30 cc, midline shift, hydrocephalus and Intraventricular extension showed significant association with mortality.   Conclusion: Hemorrhagic stroke most commonly present with symptoms like hemiparesis/ hemiplegia, headache, vomiting, convulsion and loss of consciousness. The major risk factor in the present study was hypertension followed by smoking and alcohol consumption.  Intracranial bleed in cerebellum and thalamus was associated with highest mortality. Radiologically, volume of hematoma more than30 cc, midline shift, hydrocephalus and and Intraventricular extension were associated with an increased mortality and can be used as a prognostic tool.