Trauma to a tooth during development might result in an open apex with pulpal necrosis followed by a periapical lesion. Single visit monoblock obturation with Biodentine along with a supply of growth factors through injectable plasma rich fibrin may prove useful for the predictable management of teeth with open apices. In addition, it may be considered as an alternative to the traditional apexification and obturation methods used. This report demonstrates the management of an open apex with periapical radiolucency in a maxillary left central incisor using Biodentine as an apical matrix barrier and obturating material.