Objective Describing the tumors diagnosed in patients with HIV, hospitalized in the Department of Infectious Diseases of the CHU YO.  Patients and method It was about a cross–sectional study of the prospective collection of tumors diagnosed in HIV patients hospitalized in the Department of Infectious Diseases from 1st January 2013 to 28th February 2014. All HIV–positive patients with a diagnosed tumor pathology in the department were included. Results During the study period, nine tumors were diagnosed out of a total of 55 patients living with HIV;  it represents a prevalence of 16.4%. The tumors were represented by three Kaposi diseases, three cases of post–hepatitis B carcinoma, two suspected cases of lymphoma, and one case of pancreatic head tumor. Patients were predominantly female (7/9). The average age of our patients was 41 years [33–54]. The average TCD4 lymphocyte count was 263 cells / mm3. Tumor manifestations occurred as a result of a failure of ARV treatment in three cases, as part of an immune restoration syndrome in one case, after viral hepatitis B in three patients, and in two naïve antiretroviral treatment patients . Four out of nine patients presented tumors not classified as AIDS. Four deaths were recorded, representing a lethality of 44.4%. Conclusion Post–hepatitis B carcinomas were with Kaposi‘s disease, the most frequently diagnosed.