Rationale:  Schwannoma is a benign tumor that arises from Schwann cells of the peripheral nerve sheath, and is a common tumor of the cranial nerves. Intra–parenchymal schwannomas not related to cranial nerves are very rare. To our knowledge, about 70 cases have been reported so far since the first case reported by Gibson et al in 1966. Patient concerns:  We report two cases that presented with this rare condition (Intracerebral Schwannoma), presenting with long–term history of epilepsy and headache. No associated neurological deficits. Patients had an exceptionally long preoperative observational period. These are the first cases of a supratentorial in­tracerebral schwannoma reported in Jordan, also literature review. Methods: A two female patients referred for definitive treatment of long standing history of un–controllable seizures over the last 10–years.  Neuro–radiologic screening showed intracerebral lesion with peri–tumoral edema. The patients underwent complete surgical excision. Histopathological and immuno–histochemical examination confirmed the diagnosis.  Results: We successfully treated these patients with intracerebral Schwannoma related epilepsy. They had full recovery and seizure free after 2 years. Conclusion: Intracerebral schwannoma is a very rare tumor, however it should be considered in the differential diagnosis list when a well–circumscribed small nodule with typical signal and dynamic characteristics is present. The final diagnosis should be done after histopathological and immuno–histochemical examination.