IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-6-7-11346 Original Research Paper A Rare Case of Survival From Acute Paraquat Poisoning Shah Dr. Dr.Dulari Gandhi Dr. July 2017 6 7 01 02 ABSTRACT

 Introduction

Paraquat (1, r‑dimethyl‑4,4’‑bipyridium dichloride), a brown syrupy liquid is an effective herbicide that has low chronic toxicity with poor prognosis.at present there is no specific antidote to paraquat poisoning.

Case report

A 15 years male child was admitted to the emergency room Dhiraj hospital with an alleged history of accidental ingestion of unknown quantity of paraquat at his home. He had complain of throat pain and burning sensation of throat and stomach. There were two episode of vomiting after 2 hours of ingestion. On admission he was conscious and oriented. On physical examination patient was afebrile with HR 122/min, RR 60/MIN, SPO2 85% on room air with 2 lit o2 SPO2 95% with hypertension (140/98) >95th percentile. Pupils were normal sized and B/L reactive to light. On systemic examination auscultation of lungs revealed B/L crepitation with mild respiratory distress, per abdomen hepatomegaly, and CVS examination revealed loud P2 with tachycardia. After 25 days of ingestion he developed focal seizure involving left Upper limb and left lower limb.

 

Conclusion

Paraquat a herbicide which mainly involves lungs and kidney leading to pulmonary fibrosis and acute kidney injury.  There is not specific antidote of this poison. Treatment remains supportive. Antioxidant vitamin E vitamin C and N acetyl cysteine are helpful in preventing the damage cause by free radicals. Oxigen is contraindicated in its treatment.