Fibrous dysplasia (FD) of  bone is a genetic, non–inherited disease caused by activating mutations of the GNAS1 gene which encodes the α–subunit of the stimulatory G–protein Gs. It may present as an isolated skeletal lesion (monostotic form) or involve multiple skeletal sites (polyostotic form) in addition to single or multiple endocrinoapthies.¹ McCune–Albright syndrome (MAS) is a condition which includes a classical triad of polyostotic fibrous dysplasia, Café au lait macules  and endocrinopathies.²  Whereas, Mazabraud syndrome is the term used to note the combination of FD of bone with myxomas of the skeletal muscle.¹