New perceptive theory concentrates on progesterone [PR] [t/2=30min] respiratory center stimulation   causing respiratory alkalosis, low plasma ionic calcium, smooth–muscle relaxation, generalized vasodilatation. Impact of three periovulatory PR fluctuations on ovulation is highlighted.  First preovulatory PR spurt fluctuation is due to PR accumulation as intermediary product in estrogen [ER] synthesis during negative feedback effect of 1^st ER peak and is responsible for hypothalamo – hypophyseal vasodilatation producing preovulatory gonadotropins’ surge, augments PR synthesis through explosive dominant follicular proliferation. Resultant elevated intrafollicular pressure compressing dilated thecal vessels  causes follicular wall ischemia, prevents follicular PR absorption into circulation producing  2^nd PR withdrawal fluctuation .PR withdrawal  induced  follicular vascular wall   contraction augments intrafollicular pressure squeezing  antral fluid and ovum out through stigma i.e. weakened follicular wall.  It manifests as Mittelschmerz and endometrial spotting.  3^rd postovulatory PR fluctuation due to peritoneal antral fluid PR absorption causes relaxation of already spastically contracted uterus facilitating tubal ovum suction.