IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-6-7-11419 Original Research Paper HISTOPATHOLOGICAL SPECTRUM OF ENDOMETRIAL LESIONS IN PERIMENOPAUSAL AND POSTMENOPAUSAL WOMEN IN ABNORMAL UTERINE BLEEDING. S Nithyananda Dr. Dr. Fatima Anjum Dr. July 2017 6 7 01 02 ABSTRACT

 The main aim of this study  was to evaluate aetiology of abnormal uterine bleeding in perimenopausal and postmenopausal women by histopathological examination of endometrium.

MATERIALS AND METHODS:

 A prospective study of women with abnormal uterine bleeding above the age of 40 yrs was conducted at Modern Government Maternity Hospital, Hyderabad over a period of 1 yr from June 2016 to May 2017. Endometrial samples from both D&C and hysterectomy were included in study. The specimens were processed, stained and  subjected to microscopic examination to arrive at histopathological diagnosis.

RESULTS:

A total of 450 patients were studied. Age of the patients ranged from 41 to 80years which included perimenopausal(41–49 years) and postmenopausal(50 years and above) age group.Majority of cases were from perimenopausal group. The common clinical presentation was abnormal uterine bleeding in perimenopausal group and postmenopausal bleeding in postmenopausal group. In perimenopausal group, the common finding was proliferative endometrium(21%). Hyperplasia was seen in 12% and carcinoma was seen in 0.44%.One case of tuberculous endometritis was seen .In postmenopausal group, the common finding was atrophic endometrium.Hyperplasia was seen in 18% of cases and carcinoma in 0.8%