Impetigo herpetiformis (IH) is a rare dermatoses with potential serious consequences for both the mother and fetus. Treatment is difficult and steroids is the mainstay of treatment. Cyclosporine has been used for a few cases resistant to steroids. We report our own experience in case of IH of 21 year–old woman treated successfully with tapering doses of oral prednisolone and cyclosporine in her two successive pregnancy. The disease was refractory to the oral steroids, therefore, treatment with cyclosporine was initiated and a rapid regression of the lesions was observed. Gestation was maintained, with a good perinatal outcome. Both the fetus and mother monitored closely when systemic illness occurs, as there is a risk of stillbirth. Cyclosporine, when used appropriately is effective and relatively safe.