Infantile Cortical Hyperostosis (ICH) or Caffey’s disease is a self limiting benign bone disease affecting young infants under six months of age. It is characterized by acute inflammation of the periosteum along with swelling of the overlying soft tissue in a child who presents with irritability and fever. There are a wide range of diseases disease such as osteomyelitis, scurvy, bone tumors, hypervitaminosis A and child abuse which mimick ICH ,causing a delay in reaching the correct diagnosis. The emphasis here is to remind clinicians of the very existence of the disease in this era.