BACK GROUND:

 Lipids abnormalities are major risk factors for coronary heart disease but  it is

also established as risk factor in cerebrovascular disease. The level of low–density lipoprotein (LDL) cholesterol has significant  impact on the incidence of stroke, but elevated triglycerides may also confer risk .High triglyceride levels are associated with  Ischemic strokes due to  prothrombotic state Where as  low triglyceride levels may be  a cause for  hemorrhagic strokes  due to  pro hemorrhagic state.

Objective: To study the role of  Triglycerides  in Ischemic Verses Hemorrhagic stroke 

Materials and methods:  This was an observational study conducted on 200 patients ,100 ischemic and 100 hemorrhagic strokes who were diagnosed  with computed tomography (CT) and were admitted to Osmania General Hospital between 2014–2016.A detailed history, physical examination and outcome details were collected from  hospital medical records. Data regarding fasting lipid profile, computed tomography (CT) or magnetic resonance imaging (MRI) brain reports were collected from medical records.NCEP/ATP–III guidelines and National Cholesterol Education Programme guide lines for Triglycerides were followed.

Results:  Majority of the patients with strokes were  males,with (n= 65)   ischemic strokes , (n=73)  Hemorrhagic strokes. Most of the patients were of age > 50 years. Hypertension is the most common risk factor  with  (n=64) Ischemic strokes and  (n= 76) Hemorrhagic strokes. Number of Diabetics in Ischemic strokes (n= 24) Hemorrhagic strokes (n = 20). Number of patients with hypertension and diabetes were in Ischemic strokes (n = 18) Hemorrhagic strokes (n=14).Regarding the  Lipid profile data, patients with  low HDL < 40 mg/dL  presented with  Ischemic stroke  were (n=69)and with  Hemorrhagic  stroke were  (n=56),patients with  borderline high  total cholesterol > 200 mg/dL who presented with Ischemic stroke were (n=24) and with  Hemorrhagic strokes (n=23),patients with  border line high LDL > 130 mg/dL who presented with Ischemic stroke wee  (n=47) and with  Hemorrhagic were (n=36), patients with Triglycerides < 150 mg/dL who presented with Ischemic stroke were (n=78) and with Hemorrhagic strokes were  (n=83), patiewnts with Triglycerides 150 – 199 mg/dLpresented with  Ischemic stroke were  (n=14) and with Hemorrhagic stroke wee  (n= 07), those with Triglycerides 200 – 499 mg/dL presented with Ischemic stroke were  (n=08) and with  Hemorrhagic stroke were (n=10), no patient with either ischemic or hemorrhagic stroke had Triglycerides more than 500 mg/dl.

CONCLUSION :  Present study  concludes male sex is  predominant in both types  of strokes, mean  age is lower in   hemorrhagic stroke compared to ischemic strokes .Hypertension is the common risk factor in both types of strokes. number of patients with  low HDL were   69  in ischemic stroke and 56 in hemorrhagic stroke, patients with normal range triglycerides <150mg/dl   were 83 in hemorrhagic  stroke, and  76 in ischemic stroke. Patients with  border line high   Total cholesterol   levels ( >200 mg/dl) are almost  equal  in  both types strokes   24 in ischemic  and  23 haemorrhagic stroke  .