Introduction –Nurses are a part of Swachh Bharat Abhiyaan campaign and  aims to accomplish the vision of a ‘Clean India‘ by 2 October 2019.  Health care acquired infections (HCAI) are a common complication that affects hospital treated patients because of poor basic hygiene practices. The occurrence of HCAI is a big problem in India, mostly because of a low compliance to the healthy behaviours and hygiene practice. The nurses have an important role in this campaign by informing and motivating the staff to keep a good compliance to healthy and hygiene practice.

Aim – To assess nurses’ concern regarding impacting factors on clean and healthy practice in a tertiary level hospital Uttar Pradesh, India

 Method – Data was gathered through qualitative interviews.

 Data Analysis – The interviews were tape recorded, transcribed and then analysed through content analysis.

 Results – Four main categories was identified as important for conducting a successful clean and healthy practice;  Routine activities carried out in clinical field, existing opportunities in clinical field to conduct a clean and healthy India practice, various areas to be focused and the obstacles to conduct a successful campaign.

 Conclusion – A variety of factors have an impact on clean and healthy practices. Nurses have adequate knowledge level  but is important having enough staff, sufficient material and facilities in order to bring clean and healthy India into practice.