IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-6-8-11699 Original Research Paper RANDOMISED CLINICAL TRIAL OF PRIMARY ANTIBIOTICS VERSUS SURGERY IN CASES OF ACUTE APPENDICITIS MUSTAFA Dr. August 2017 6 8 01 02 ABSTRACT

 Recent advancement in diagnostic technology and availability of effective antibiotics provide us an opportunity to revise our approach in the management of acute appendicitis. This clinical trial was done on 200 patients of acute appendicitis, according to set criteria, 20% underwent primary surgery  and 80% primary conservative (antibiotics) treatment. 90% of those treated conservatively recovered, 10% needed surgery within 48 hrs. due to treatment failure and 11.25% were operated for recurrence during one year follow up.

Conservative (Antibiotic first) approach is safe in majority of the cases, immediate surgery in all cases of acute appendicitis is not rationale and should be revised.