Peptic ulcer is one of the commonest diseases of GIT. Two main types are gastric and duodenal. In India ratio of duodenal to gastric ulcer is 30:1 (Rains & Mann – 1984). Duodenal ulcer is predominantly a disease of adult males. The aim was to find out the risk factors for the development of the leakage after simple closure of duodenal ulcer and to assess the association of clinical predictors associated with higher number of complications. The materials for the present work comprised of patients with perforated duodenal ulcer admitted in my department through surgical emergency of Patna Medical College and Hospital between the periods from August 2014 to July 2017.