IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-6-8-11893 Original Research Paper VITAMIN D LEVELS IN EARLY PREGNANCY & PREGNANCY OUTCOMES Lata Rajoria Dr. Dr Sunita Hemani Dr. Dr Dolly Marwai Dr. August 2017 6 8 01 02 ABSTRACT

  

Aims and objectives – To find out the correlation of serum Vitamin D levels in early pregnancy and pregnancy outcomes (i.e. development of preeclampsia, birth weight, apgar score and NICU admissions etc.).

Material methods – This is a hospital based observational study done in Department of Obstetrics &   SMS Medical College, Jaipur from March 2015 to Oct 2016 on 800 pregnant women attending the Antenatal clinic between 13–20 weeks gestation. Serum Vitamin D levels were assessed, all women were followed till delivery and three days after delivery.

Results – Serum 25(OH)D concentrations in early pregnancy were lower in women who subsequently developed preeclampsia as compared to women who did not developed preeclampsia [mean, 13.58 ± 7.61 ng/ml, vs. 17.14±6.91ng/ml], Mean birth weight of newborns where the mothers was Vitamin D deficient came out to be 2.205 ± 0.44 kg, for insufficient mothers mean birth weight was 2.59 ± 0.407 kg while the mean birth weight was 2.83 ± 0.49 kg in newborns of Vitamin D sufficient mothers. When APGAR score of neonate at 5 minute ≥7, mean maternal Vitamin D was 17.31 ± 6.99 ng/ml whereas when APGAR score of neonate at 5 minute was < 7, mean maternal Vitamin D was 13.48 ± 6.99 ng/ml. Mean maternal vitamin D level was 17.27 ± 6.903 ng/ml in newborns who did not require NICU admission, whereas it was 13.87 ± 7.22 ng/ml in those who required NICU admission.

 

 

Conclusion – Thus we conclude that Low serum Vitamin D levels in early pregnancy is associated with increased incidence of Preeclampsia low birth weight, low apgar score and increased NICU admissions.