Vitamin D has an important role to play in skeletal and extraskeletal health. It has been estimated that 1 billion people worldwide have Vit D deficiency or insufficiency¹. Vitamin D deficiency prevails in epidemic proportions all over the Indian subcontinent, with a prevalence of 70%–100% in the general population. Vitamin D deficiency can lead to serious consequences like hypocalcemic seizures and increased risk of respiratory tract infections in neonates and infants and mental retardation². Patients may present with hypocalcemic seizures even in the absence of subtle hypocalcemic signs³. The following is a rare case of first seizure as a manifestation of hypocalcemic secondary to severe vitamin deficiency in a 14yo patient with mental retardation. All treatable metabolic conditions should be excluded at first before commencing treatment with anticonvulsants as this will prevent patients from burdensome polytherapy and related side effects.