Latent autoimmune diabetes in adults (LADA) accounts for 2%–12% of all cases of diabetes. Patients are typically diagnosed in young adults and are often misdiagnosed as type II DM. The aim is to study the association of GAD–65 autoantibodies as a marker in the diagnosis of LADA and to compare the clinical parameters, & metabolic factors in diabetic Patients. We studied 300 diabetic patients. A multiple regression was run to predict role of GAD 65 antibodies in LADA diagnosis from Age, HbA1c, BMI, Cholesterol & C–peptide.  These variables statistically significantly predicted GAD 65 antibodies, P < 0.5. The results of our study in a diabetic population revealed that the prevalence of  LADA (17.3%). while some anthropologic characteristics can be useful for the preliminary screening of LADA patients in a diabetic population, GAD 65 autoantibodies determination can be considered as confirmatory diagnostic markers for LADA.