Sjögren‘s syndrome, either primary or secondary, has been defined as an autoimmune epithelitis characterized by lymphocytic glandular infiltration and various extraglandular manifestations. It shows an intense T lymphocyte mediated autoimmune process in the glands as one of its most prominent components, owing to dry eyes (xerophthalmia) and dry mouth (xerostomia). It can exist by itself (Primary Sjogren’s syndrome or Sicca syndrome) or develop in association with another connective tissue disorder (Secondary Sjogren’s syndrome). The syndrome has many dental implications that are important for the dentists. We present a case on secondary sjogren’s syndrome and a brief note on its etiopathogenesis.