Background – Platelet volume indices are routine parameters provided by any automated hematology analyser. Increased platelet activity can be diagnosed by raised platelet volume suggesting increases prothrombotic state which is associated with adverse outcomes in intensive care patients. Advancements in health care facilities are now focusing on identifying new predictors of clinical outcome of patients with critical illness. Newer indices such as presepsin and soluble CD 14 subtype can be used but are expensive. Platelet volume indices are and hence be used for routine monitoring and assessing the risk of mortality in intensive care patients. Objective –The objective was to to study the correlation between platelet volume indices and mortality in intensive care unit patients. Methods –This was to retrospective case control study conducted in a tertiary 14 bed Intensive care unit(ICU) with a sample size of 65 non survivors(cases) and 130 survivors(controls).

Results – Multivariate logistic regression analysis was done and only hemoglobin at admission was the only predicting factor with low haemoglobin level associated with increased mortality with Odds ratio: 0.793 and p value 0.002. Pearson’s Correlation was calculated between MPV and other parameters and a moderate positive correlation was found between MPV and Plateletcrit with Pearsons’s correlation coefficient: 0.262 and PLCR. In conclusion there was no correlation between platelet count and other platelet indices on admission to ICU with mortality. Hemoglobin was found to be the only significant indicator in assessing mortality in ICU patients. However prospective studies need to be done on not only platelet indices at admission but serial platelet indices before ruling out use of platelet indices in assessing mortality in ICU patients.