Aim:  To evaluate the effect of Metformin on periodontium in Type 2 Diabetes patients.

Materials and Method: 30 subjects (Type 2 Diabetes) were included in the study. Subjects were divided into Metformin and Non Metformin groups. Fasting blood sugar (FBS) levels and Russell’s Periodontal Index (RPI) were assessed. Radiographic assessment was done using OPG to confirm findings of RPI. Measurements were recorded and subjected to statistical analysis.

Results: There was a statistically non–significant difference seen in the mean FBS between the Metformin & Non–Metformin groups (p>0.05), the mean being slightly higher for the Non–Metformin group. There was a statistically non–significant difference seen in the mean RPI between the two groups(p>0.05), the mean being slightly higher for the Metformin group.

Conclusion: Metformin, though an anti–hyperglycaemic , does not have a significant beneficial effect on human periodontium, within the limitations of the study.