IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-6-9-12013 Original Research Paper EFFECT OF OBSTRUCTIVE SLEEP APNEA ON LIPID PROFILE. kumar sah Dr. Dr. Aloke Banerjee Dr. September 2017 6 9 01 02 ABSTRACT

 OBJECTIVES:– To find the difference in BMI, total cholesterol(TCH), triglyceride (TG), high–density lipoprotein (HDL Cholesterol), VLDL Cholesterol, and LDL Cholesterol among participants of  AHI>10 group and AHI≤ 10 group.

METHOD: Two groups were made, AHI>10 group having 25 participants and AHI≤10 group having 25 participants on bases of severity of sleep apnea recorded by polysomnography. Their height was measured with help of mounted measuring tape, weight was recorded using digital weighing machine, followed by calculation BMI, fasting blood sample was collected in morning around 6.30 am after recording of polysomnogram for lipid profile . Then comparison of all these parameters was done among the participants of the AHI>10 and AHI≤ 10 groups.

RESULT: Mean BMI of participants in AHI>10 group was more as compare to mean BMI of participants in AHI≤10 group and the difference was highly significant. Mean TG of participants in AHI>10 group was significantly higher as compare to mean TG of participants in AHI≤10 group . Mean LDL of participants in AHI>10 groups was significantly higher as compare to mean LDL of participants in AHI≤10 group.

CONLUSION:  In this study we have concluded that increasing severity of OSA (obstructive sleep apnea) causes significant increase in level of TG and LDL cholesterol in serum of these participants.