ABSTRACT

IJSR

International Journal of Scientific Research

2277 - 8179

Indian Society for Health and Advanced Research

ijsr-6-9-12063

Original Research Paper

A establishments of relationship between Parathyroid Adenoma and Pathological Fracture (Incidental)

Himanshukumar

V. Patel

Dr. Dr.

Meemansha Buch

Dr. Dr.

P.N. Palat

Dr.

September 2017

6 9 01 02 ABSTRACT

Parathyroid Adenoma is the common cause of primary hyperparathyrodism present with mostly asymptomatic Hypercalcemia. In present case report we describe a case of Adenoma with Hypercalcemia and Pathological Fracture.

– Parathyroid Adenoma lead to excessive secretion of PTH (Parathyroid Hormone).

– PTH is 84 Amino acid single chain peptide

It act by maintain the Ca–Homeostatic mechanism by – direct action on the Bone and Kidney.

– By ↑ Catt & ↓ Phosphate & Indirectly â¦action–↑ Vitamin – D

In case of Parathyroid Adenoma ↑↑ PTH → lead to bone resorption & release calcium & Phosphate excretion – ↓ Bone Density & Hyaercalcemia ↑ incidence of Pathological Fracture