IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-6-9-12065 Original Research Paper Correlation of Pap Smear with histopathological findings in Malignant and non–Malignant lesion of cervix Shrivastava Dr. September 2017 6 9 01 02 ABSTRACT

 Cervical carcinoma is major health problem worldwide. Conventional cervical cytology is the most widely used cervical cancer screening test in the world. Aim and Objective:To classify cervical lesions into malignant & benign groups and to correlate the cytological with histopathological findings. MATERIAL AND METHOD– This is a prospective cross–sectional study done in NMCH, Patna , between  October 2015 to march  2017, Department of Obstetrics and Gynaecology.. During the period, all the samples of  Pap smear  taken in Gynae OPD  were studied. 200  cases who had   abnormality in Pap smear and  undergone both Pap smear and cervical biopsy (including hysterectomy sample) were included in the study The cytological interpretation of the smears was made according to the new 2001 Bethesda system.

RESULT–In my study  most of the women(40%)   were 31–40 years of age  followed by 41–50 years of age (38%).Mean age was 41 years.  Unsatisfactory smear was found in 4% cases, inflammatory smear in 59.5 cases, ASCUS in 5% cases, LSIL in 9% cases, HSIL in 10% cases , frank malignancy in 12.5% cases. In biopsy report  5.5% of cases had normal histology report. In  58.5%  cases  infection (chronic  cervicitis)was present. Carcinoma reported in 22.5% cases, CIN 1 in 3.5%, CIN 2 IN 4%, CIN3 in 3% cases and  benign tumor in 3% cases. Pap smear shown good correltion with histopathology report.conclusion– Pap smear is cheap, simple , non invasive  and effective method for early detection of premalignant and malignant lesion of cervix and it shows good correlation with histopathology report.