In this study, the antimicrobial activity of 40 amniotic fluid samples had been examined. Relationships were also examined between the antimicrobial activity of the amniotic fluids and maternal age, gestational week, number of birth, number of gestation and karyotype.

Thirteen (32,5 %) of 40 amniotic fluid samples showed inhibitory effect on  Escherichia coli,  and 3 (7.5%) on Candida albicans. Both E. coli and C. albicans was not effective in the sample. According to the results, there were no significant statistical relationship between the antimicrobial activity and maternal age, gestational week, number of birth, number of gestation, karyotype. In this study, a total of 40 amniotic fluid samples from mothers between 16–18  weeks gestation.