Introduction: Wound infection is one of the most common and serious complications among the hospital acquired infections Wound infection can increase the length of hospital stay and accounts for the mortality rate up to 70–80%.

Aim & Objectives: The objective of present study was to determine the  Bacteriological profile and antimicrobial sensitivity pattern of organisms  isolated   from  pus samples

Materials & Methods: 200 pus samples collected from March 2017–August 2017  were processed in the  Microbiology  service laboratory

 Results: Out of 200 samples 50% had growth and were processed.AST  performed by Kirby–Bauer disc diffusion method. GNB showed 70% and GPC 30% growth. E.coli among GNB and Staphylococcus among GPC were common

Conclusion: Early recognition of lesion and prompt initiation of antimicrobial therapy is essential. Antibiotic susceptibility test is a prerequisite for the management of infections which can help to make better therapeutic choices.