Acrokeratosis verruciformis of Hopf is a rare genodermatosis characterized by keratotic lesions on the dorsum of the hands and feet. Lesions are usually present from birth or early childhood, but some cases in adult life are reported. It affects both sexes. It usually presents at birth or appears in early childhood; however the onset may be delayed until fifth decade. Patient will present with complaints of hyperkeratotic, skin colored, flat, verrucous papules appear on the dorsal aspect of hands and feet, and sometimes on the forearm, elbows, knees, and face as well.