IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-6-10-12396 Original Research Paper Hyponatremia in patients with cirrhosisOriginal Article Sangeeta Dr. October 2017 6 10 01 02 ABSTRACT

 Hyponatremia is a common problem in patients with advanced cirrhosis and portal hypertension1.The severity of the hyponatremia is related to the severity of the cirrhosis.It  is characterized by excessive renal retention of water relative to sodium due to reduced solute–free water clearance2. The primary cause is increased release of arginine vasopressin. Hyponatremia is associated with increased mortality in cirrhotic patients, those with end–stage liver disease (ESLD) .Clinical evidence suggests that adding serum sodium to model for ESLD (MELD) scoring identifies patients in greatest need of liver transplantation by improving waiting list mortality prediction3.