Immune thrombocytopenic purpura (ITP) is an autoantibody–mediated thrombocytopenic disorder in which accelerated destruction of platelets occurs; platelet production may also be impaired by these antibodies. ITP is characterized by mucocutaneous bleeding. Rarely, more severe haemorrhages, such as intracranial haemorrhage, may occur. A female patient, she had the history of ITP and CLD produce intracranial haemorrhage and which was diagnosed from radiological examination. Treatment given to the patients includes cognitive enhancers, hemopoietic agents and hepatic protestants.