IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-6-11-13201 Original Research Paper A comparative study between desflurane and sevoflurane in pediatric anaesthesia with laryngeal mask airway Lulu Fatema Vali Dr. Dr. Abhay Rathod Dr. November 2017 6 11 01 02 ABSTRACT

 

Aims and objectives: Our study compared desflurane with sevoflurane maintenance anesthesia in terms of respiratory events and the emergence characteristics in children with a laryngeal mask airway.

 

Methodology: This randomized controlled trial evaluated 200 children undergoing strabismus surgery allocated to desflurane or sevoflurane groups. After inducing anesthesia with sevoflurane and thiopental sodium 5 mg kg−1, the anesthetic agent was changed to desflurane in the desflurane group, whereas sevoflurane was continued in the sevoflurane group.

 

Results: The overall respiratory events did not differ between the groups. However, the incidence of mild desaturation (90% ≤ SpO2 < 97%) was significantly higher in the desflurane group (7%) than in the sevoflurane group (0%) (P = .007). Emergence was significantly faster in the desflurane group (6.6 ±â€Š3.9 vs 8.0 ±â€Š2.2 min, P = .003).