Background: Platelet Transfusions are life saving, so their appropriate usage ensures uninterrupted supply.

Aim: Audit for appropriateness of 1000 units of platelet transfusions in a tertiary care hospital of North India.

Materials and Methods: Platelet audit of 1000 units was carried out in year 2012–2013 to estimate its appropriate utilization. These were analyzed according to the age and sex of the patient, pre–transfusion platelet count, associated risk factors, bleeding status, indication and specialty from which transfusion was requested. Data was analyzed according to the British Committee for Standards in Haematology guidelines for their appropriateness.

Results: Out of total 1000 platelet units transfused to 216 patients in 284 transfusion episodes, 83.9% of overall platelet transfusions were appropriate, 77.8% prophylactic and 98.6% therapeutic transfusions were appropriate. Maximum appropriateness was seen in obstetrics & gynaecology (97.97%) and minimum in Pediatrics (75.6%).

Conclusions: Regular audit of platelet transfusions and sensitization of the clinicians regarding triggers for appropriate platelets usage will ensure maximum appropriate utilization of platelets.