Cancer is a major public health problem affecting populations worldwide . The disease is well known for its Geographic variations at various levels. A retrospective study of Cancer pattern was done in a tertiary care hospital, South India. The cases were grouped according to gender, age and sites of cancer and the findings were  presented and compared with existing literature. It was observed that 43.2% of all cancer cases were males and 56.8% were females with a male female ratio of 1:1.3. The commonest age group affected in men and women were 60–69 and 40–49 years respectively. Stomach and Breast were the most common sites of cancer pattern in men and women respectively reported our Institution. Studies that provide an idea about Cancer pattern in a particular area help to plan hospital facilities for patient care and also find the potential areas of clinical and epidemiological research of practical importance.