Background: The Study entitled “Comparative analysis of graft placement medial or lateral to the handle of malleus in inlay technique of myringoplasty in terms of graft take–up rate, hearing improvement and complications”.

Methods: Prospective randomized single blind study on 52 patients (age 18–40 years) who had dry, central, medium sized perforation secondary to Chronic Otitis Media(mucosal disease) were included in our study. The patients were divided into two groups. Group A (23 patients) in whom graft was placed medial to the handle of malleus and group B (29 patients) in whom graft was placed lateral to the handle of malleus in modified inlay technique of myringoplasty.  

Results: The results of the two techniques were compared in terms of graft take–up rate, hearing improvement and complications at the end of 6 month follow–up. The graft take–up rate and post operative gain in air conduction in group A was 91.30%, 3.57+/–6.61 dB ( mean+/–SD) respectively and it was 96.55%, 6.62+/–6.86 dB (mean+/–SD) respectively in group B (p value is >0.05). Which were statistically analysed by Chi–square and T–test.  Conclusion– We concluded that there is no difference in graft take–up rate, gain in hearing or complications in both the techniques, in consideration of the duration of surgery, technicality and healing, placement of graft lateral was found to be better than medial to the handle of malleus in modified inlay technique of myringoplasty.